Biosynthetic pathways of the most abundant cannabinoids

During the biosynthesis of various phytocannabinoids, cannabigerolic acid (CBGA, 1) serves as the key branching point for a number of cannabinoids such as Δ9-THC (7), CBD (9), cannabielsoin (CBE, 16), cannabichromene (CBC, 10), and cannabicyclol (CBL, 11) families of phytocannabinoids.
Δ9-Tetrahydrocannabinol (Δ9-THC) is transformed into CBN (12) through an oxidative aromatization, and CBN can in turn be photochemically rearranged into the catechol, cannabinodiol (CBND, 13).
Lewis et al., 2017 [7]

2 thoughts on “Biosynthetic pathways of the most abundant cannabinoids”

  1. Could you please share the full citation for Lewis et al., 2017? I’m having trouble finding the article from which this image is sourced.

    1. Lewis et al. 2017. Chemical Profiling of Medical Cannabis Extracts. ACS Omega 2017, 2, 6091−6103 DOI: 10.1021/acsomega.7b00996

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